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Today, over 100 million Americans suffer from at least one chronic disease. With no cure, our friends and families are leashed to treatments that address symptoms rather than root causes.
Our aim is to slash incidence rates of disease in the next generation. We detect risk at the earliest stages, and give couples the ability to tilt the odds toward extending their children's healthspan - the number of years of life uninterrupted by disease.
Orchid is a reproductive technology company working to give everyone the ability to have a healthy child. We are doing the difficult work of measuring and mitigating genetic risk—so the next generation can concentrate on life, not managing a disease.
We're building ultra high resolution genetic reports so that, for the first time in human history, prospective parents can protect their future children from inheriting a predisposition to the most common diseases -- not just rare ones.
All roles are remote-friendly. We are based in San Francisco.
The opportunity to have a trajectory-altering impact on humanity
The opportunity to grow rapidly and influence engineering, product, and the strategic direction of the company.
Competitive compensation (base, equity, generous benefits)
Remote
We are looking for a remarkable statistical geneticist that enjoys being self-directed and identifying the most important problems to solve.
You will:
Lead the development, validation, and translation efforts to deploy polygenic risk scores into clinical reports.
Use cutting edge statistical approaches, large datasets (public and privately obtained through collaborations) to build workflows and processes that ensure high quality results are returned consistently.
You have:
A PhD in a quantitative or computational field (statistics, genetics, computational biology, or similar)
A demonstrated ability to use and develop cutting edge methods for analyzing human genetic data
You are:
You (may) have:
A track record of translating scientific results into new products
Successfully recruited and built great teams
To apply, send an email to Noor at noor@orchidhealth.com with the subject line "Senior Statistical Geneticist". Please include 2-3 bullet points on your most significant technical contributions to a recent publication, and links to help us learn more about yo (Google Scholar, GitHub, personal website).
Remote
We are looking for an engineer who loves building complex systems. We value people who can quickly obtain a deep technical understanding of new domains, and enjoy being self-directed and identifying the most important problems to solve.
You will:
Work collaboratively with our lab leadership to provide timely bioinformatics support with attention to detail and clear communication; build repeatable and automated processes when possible
Define a system to organize our validation samples and how they should be used as our company scales (wet lab protocol adjustments; higher case volume, etc)
You have:
Masters degree or equivalent industry experience in Bioinformatics, Computer Science or a related field, additional industry experience preferred
Expert status in whole genome sequencing analysis
You (may) have:
Strong track record of independence, innovation, and productivity demonstrated through multiple peer-reviewed publications, grants, or patents
To apply, send an email to Carly at carly@orchidhealth.com with the subject line "Bioinformatics Engineer". Please include links to help us learn more about things you've built (GitHub, GoogleScholar, personal website, LinkedIn).
Remote
We are looking for a strong generalist that is interested in exploring technical problems in a variety of domains, such as front-end, backend, machine learning, performance, infrastructure, or web technologies in general. We want this person to be radically ambitious and eager to make an impact. If you are enthusiastic about any of the following — the company, biotech, genetics, health, startups, or becoming the best version of yourself — this is the place for you.
You will:
Work in cross-functional teams to architect and build features that will create the most value for users
You have:
Experience building software products that impact users
Willingness to debug problems across the stack, scuh as performance problems and deployment issues
You (may) have:
2+ years of experience with UX development or web services and application development
2+ years of experience in web development (frontend or backend), machine learning, or infrastructure engineering
To apply, send an email to Noor at noor@orchidhealth.com with the subject line "Software Engineer - Generalist". Please include links to help us learn more about things you've built (LinkedIn, GitHub, personal website).
Remote
We are looking for an engineer who loves building complex systems. We value people who can quickly obtain a deep technical understanding of new domains, and enjoy being self-directed and identifying the most important problems to solve.
You will:
Work with our statistical geneticist to select and validate genetic risk scores
Conduct analyses of large-scale genetic data to understand patterns of disease risk in large populations
You have:
Experience working with or developing complex production systems that involve large volumes of data
A willingness to dive deep into data to understand patterns and anomalies in genetic data
You (may) have:
Experience analyzing "big data" or scientific data
A solid understanding of good experimentation practices for solving applied research problems
To apply, send an email to Noor at noor@orchidhealth.com with the subject line "Senior Research Engineer - ML". Please include links to help us learn more about things you've built (LinkedIn, GitHub, personal website).
Remote
You can transform raw ideas into product designs. You care deeply about user experience and have excellent visual design skills. You are a self-starter, self-motivated, and able to execute even when sometimes given very broadly defined, loose projects ideas.
You have:
Expertise in either UI, UX, or visual design, and skilled in more disciplines across product design
Enjoy striking a balance between functional and aesthetic design
You (may) have:
- Experience as an early-stage founder, or enjoy fast-paced work environments with tight feedback loops
To apply, send an email to Noor (CEO) at noor@orchidhealth.com with the subject line "Working at Orchid: Designer". Please include links to help us learn more about things you've designed (Dribbble, personal website/portfolio).
Remote
Lead growth and digital marketing for a company changing how we conceive. Orchid allows couples to change the trajectory of their future child's health with the highest resolution genetic reports + embryo prioritization.
You will be charged with:
(1) growing our customer base / sales
(2) managing all paid channels
(3) optimizing retention activity
(4) managing / leading all agency, in-house, and contracting resources.
This role will require you to design, measure, and test the impact of all potential channels for acquiring users. You'll flex your creative side as well as your analytical and metrics-driven nature. Furthermore, outside of digital marketing you will shape Orchid's product, brand image, PR, partnerships, and more.
You are:
- Creative, quantitative, scrappy, diligent, and ruthless.
You have:
A track record of leading major, measurable wins.
3+ years in Growth/Performance Marketing at growth-stage or early-stage tech companies
You (may) have:
- Experience as an early-stage engineer or founder, or enjoy fast-paced work environments with tight feedback loops
To apply, send an email to Noor (CEO) at noor@orchidhealth.com with the subject line "Working at Orchid: Head of Growth". Please include 2-3 bullet points quantitatively describing your wins in a prior role.
Remote
You can author, promote, and distribute content that engages and educates customers. You are analytical and process-oriented in measuring growth and conversion. You are a self-starter, self-motivated, and have enough experience to tell us what we need to do to be successful.
You have:
Experience managing social media and content strategy AND execution
Experience using metrics to test and refine content strategy, discover new channels, and allocate where marketing resources will yield highest return
To apply, send an email to Noor (CEO) at noor@orchidhealth.com with the subject line "Working at Orchid: Director of Communications". Please include links to help us learn more about you (writing portfolio, LinkedIn, personal website).
Remote
We are looking for a ludicrously effective person to join our team as a cross-functional player putting out fires as they crop up. The ideal candidate is strategic, a systems thinker, and thrill seeker excited to be exposed to all aspects of the business, and unphased by taking on daunting new projects each day.
You can:
Deliver results consistently under a tight timeline. Given an ambiguous, exploratory task, you can quickly come up with a strategy and process around getting answers back to the team. You are an unrivaled individual contributor, but you can also sense when it makes more sense to hire out a piece of a project. You can draft a brief, source applicants, interview, hire, and manage a project from vague inception to decisive completion.
Become an expert on a new topic quickly. You know how to acquire knowledge in a new domain - what to read, where to look, who to talk to.
You (ideally) have:
- A technical degree (engineering, sciences)
- Experience as an early-stage engineer or founder
- High grit and low ego
To apply, send an email to Noor (CEO) at noor@orchidhealth.com with the subject line "Role at Orchid: Director of Special Forces". Please include 2-3 bullet points describing something you pulled off faster and/or with a lower budget than anyone thought imaginable. Also include links to help us learn more about you (writing portfolio, LinkedIn, personal website).
Location: North Carolina
The Molecular Laboratory Technologist will perform advanced molecular diagnostic testing using cutting-edge technologies. This role focuses on high-throughput sequencing, nucleic acid isolation, and other molecular biology techniques to support clinical diagnostics. Given our commitment to serving patients in New York State, this position requires strict adherence to New York State Department of Health regulations, including compliance with Clinical Laboratory Evaluation Program (CLEP) standards, as well as CAP and CLIA guidelines. An active New York State Clinical Laboratory Technologist License is mandatory for this role.
This is a full-time, on-site position based in North Carolina, with rotating weekend coverage as part of the schedule.
You will:
Molecular Testing & Analysis
- Conduct all aspects of a typical NGS workflow, including DNA amplification, purification, library preparation, library quantification, and sequencing.
- Operate and maintain Illumina sequencing platforms ensuring accuracy and efficiency.
- Perform routine experiments utilizing established protocols, identifying and resolving issues during procedures.
- Analyze and interpret sequencing data, preparing accurate and detailed documentation.
- Assume responsibility for the accuracy, quality, and timeliness of experimental results, summarizing and reviewing outcomes with the supervisor.
Quality Control & Compliance
- Conduct routine environmental monitoring and quality control required for CLIA, CAP, and New York State CLEP compliance, including recording freezer and refrigerator temperatures, humidity levels, and more.
- Perform daily QC and reagent lot QC, documenting and evaluating results per SOPs.
- Troubleshoot instrumentation and workflow issues to maintain operational efficiency.
- Participate in lab inspections, ensuring adherence to safety standards and regulatory compliance.
You have:
- Bachelor’s or master’s degree in molecular biology, Biochemistry, Genetics, or a related discipline.
- ASCP Certification preferred
- Minimum of 2 years of experience in a high-complexity molecular diagnostics laboratory.
- Proficiency in molecular biology techniques, including DNA/RNA isolation, PCR amplification, and NGS library preparation.
- Hands-on experience with Illumina sequencing platforms(e.g., NovaSeq6000) and NGS workflows preferred.
- Expertise in LIMS and other laboratory data management systems.
- Knowledge of NGS data analysis and interpretation is an advantage.
- Familiarity with automated liquid handling systems is a plus.
- Strong organizational, communication, and problem-solving skills.
- High attention to detail and commitment to quality.
Application Process:
If you’re passionate about molecular diagnostics and want to contribute to groundbreaking advancements in healthcare, we encourage you to apply. Submit your resume and a cover letter detailing your experience and interest in this role to ahmad@orchidhealth.com
We're a low-ego team of optimistic builders who care deeply about helping every couple have a healthy baby, and we’re looking for exceptional individuals to join the team.
At Orchid, we're working on bringing a new capability for humanity online - the ability to measure and mitigate genetic risk for the diseases that matter most. Instead of health being a genetic lottery at birth, we want every prospective parent to have the information and choice to protect their child from inheriting health risks.
Having a child is a big step in life. Your work directly contributes to a life altering moment for prospective parents and has the potential to bend the trajectory of a child's life toward a healthier future.
In 1990, we started without the ability to even read the 3.2 billion letters in the human genome. We spent 13 years and $3 billion dollars assembling the very first sequence. Since then, the cost of sequencing has plummeted, enabling millions of human genomes to be assembled, often paired with physician-verified diagnoses. The goal of genomic medicine is on the cusp of realization - we have a newfound ability to measure genetic susceptibility for the most common diseases.
Historically, we haven't been able to move beyond rolling the dice to determine health outcomes in the next generation. Be a part of defining a fundamentally new category of precision medicine. Today, we have the opportunity to give parents high resolution data to stack the odds in their child's favor - against diseases that have burdened families for generations.
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Orchid is backed by the top founders in technology and health - including the founders of Coinbase, Counsyl, 23andMe, Flatiron, Eventbrite, Oscar, and Clover - as well as Refactor Capital, Day One Ventures, and Village Global.
